Abstract: Developmental theory indicates that success during a major life change requires attention to multiple life domains (e.g., physical health, mental health, employment, financial, and social). This study presents a revised conceptual framework and offers a new empirical model to assess the well-being of post-9/11 veterans as they transition to civilian life. Data from a large sample of post-9/11 veterans surveyed over 2.5 years revealed that post-9/11 veteran transitions were mixed: veterans improved over time in some domains (e.g., employment), stagnated in some (e.g., social), and struggled more over time in others (e.g., physical health). Even in domains with improvement, a large percent of veterans still struggled (e.g., 34% struggled with mental health at Wave 6). Moreover, certain groups tended to struggle more (e.g., enlisted, women, people of color). The conceptual framework and empirical model are intended to stimulate discussion on how best to understand, evaluate, and support veterans' military-to-civilian transition.