Abstract:This study examines the use of ibogaine followed by 5-MeO-DMT for treating PostTraumatic Stress Disorder (PTSD) in special operations veterans, focusing on the subjective experience and therapeutic efficacy of these substances. Twelve participants underwent semistructured interviews, with five follow-ups conducted. Long-term data (10 months to three years post-treatment) was available for eleven participants. Using a constructivist grounded theory approach, the analysis explores participants’ motivations, treatment experiences, and outcomes. The researcher introduces the theory of gnosis to explain the sustained positive effects observed in all participants. Efforts were made to identify individuals with negative or harmful outcomes, but none were found. Findings have significant implications for psychedelic-assisted therapy (PAT), PTSD treatment, and the broader application of psychedelics in mental health care.